evaluation of anti-inflammatory and membrane stabilizing property of ethanol extract of cansjera rheedii j.gmelin (opiliaceae)

cansjera rheedii is widely used as a traditional medicine for the treatment and control of a variety of human inflammatory ailments by the fishermen of auroville.   in the present study, the anti-inflammatory and membrane stabilizing property of ethanol extract of cansjera rheedii j. gmelin (eecr) was evaluated in rat using the human red blood cells (hrbc) membrane stabilization method and carrageenin-induced acute paw edema model.   the extract in concentration of 6-100µg/ml showed a dose-dependent inhibition of haemolysis of erythrocytes induced by hypotonic solution.   oral pre-treatment with eecr (250mg/kg) inhibited carrageenin-induced paw edema (41.93%) within 3 hrs.   it is concluded that the extract possess anti-inflammatory as well as membrane stabilizing property.